Qualitative ablation

Dandbital intelligence, surgical robotics, navigation systems makes difficult tasks easier, allows specific movements to be performed accurately, and theoretically reduces the likelihood of mistakes. interventionis Radiologytion usesmos Robotic or semi-robotic systems have been developed for the treatment of tumours, which allow precise positioning of the needle, prediction of the future treatment field, evaluation of the effect of the procedure here and now in the operating theatre, and additional steps if needed.

High-quality ablation with AI-guided navigation allows for a restorative and standardised tumour treatment, leading to better outcomes for more cancer patients.

By 2030. diagnoses will be made worldwide every year
around 10-11 million. cancer cases (WHO).

The incidence of oncological diseases is increasing in Lithuania, but the same trend is also observed in other countries around the world. Cancer is an age-related disease, so as life expectancy increases and the population grows older, so inevitably does the number of oncological diseases.

Lithuania has one of the highest cancer mortality rates compared to other European countries. Cancer mortality is directly related to changes in incidence and the effectiveness of treatment.

Artificial intelligence in cancer diagnosis and treatment

Cascination – developers of innovative medical systems, providing the highest quality products, support and fast problem resolution. CAS One IR system with integrated software AblaSure. This is is an artificial intelligence trained to use large datasets toSeeinstant, seamless and trithree dimensions to estimate effective ablation thresholds based on from anksto the treatment plan you have developed. This DThe I-based algorithm additionally calculates the coverage percentage, indicating the extent to which the tumour and the target threshold have been removed.

IoT navigation system

AmberCell Solutions is working with Cascination, the Swiss manufacturer of one of the most innovative IoT navigation systems CAS One IR. This company – developers of innovative medical systems, providing the highest quality products, support and fast problem resolution.

CAS One IR system with integrated software AblaSure. This is is an artificial intelligence trained to use large datasets toSeeinstant, seamless and trithree dimensions to estimate effective ablation thresholds based on from anksto the treatment plan you have developed. This DThe I-based algorithm additionally calculates the coverage percentage, indicating the extent to which the tumour and the target threshold have been removed.

The economic impact of qualitative ablation at societal level

Saving the institution’s money with IoT-controlled navigation systems

The IoT navigation system reduces procedure times, human error, efficiency and workload. The time saved on the equipment can be used for other procedures. From an interventional radiology perspective, DI is useful in several ways. Firstly, in the planning of procedures, tools such as virtual reality allow pre-procedural planning, accurate assessment of complex anatomy or simulation of the procedure and its outcome, without any potential risk to the patient.

Using the IoT navigation system

Artificial intelligence is used in navigation systems used in combination with thermal and non-thermal tumour ablation (tumour destruction) devices. This helps doctors to more accurately assess the size and localisation of the tumour, plan the procedure, and immediately assess whether the result has been achieved after the procedure is finished.

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Microwave ablation

Tumour destruction using heat generated by microwave energy

Radio
frequency ablation

The tumour is disintegrated by exposure to low temperatures

Electro-Corporation

A combination of electrical pulses and anti-cancer drugs.

Cryo
ablation

The system uses medicines gas, which helps to reach extremely low temperatures, freezing the tumour and then thawing it

Biopsies

An interventional method of testing in which a piece of biological cells or tissue is taken for examination from sites where abnormalities are present

Microwave ablation

Microwave ablation – (MWA) is the destruction of a tumour using heat generated by microwave energy. CT or UG is used to pinpoint the exact location of the tumour and for evaluation. Microwave generators have the ability to use thin needles, also known as antennas, through which microwaves are fed from the generator. The antennas are inserted into the tumour through the skin and can also be used during open surgery.

AmberCell Solutions can offer a TATO device that uses up to four antennas at the same time, which is extremely easy to operate, ergonomic and ensures a safe procedure. The system can be used for the thermal destruction of tumours in the liver, kidneys, lungs, thyroid, bone and other organs. Procedures are reimbursed for liver and thyroid tumours and partially reimbursed for kidney, lung and other organs.

Frost ablation

Cryo ablation is a thermal percutaneous tumour ablation technique in which cryoprobes (antennas) are introduced into the tumour under CT guidance. The system uses a medical gas to reach extremely low temperatures, freezing the tumour and then thawing it. When exposed to low temperatures, the tumour is destroyed. Up to eight antennas can be connected at the same time, depending on the size of the tumour. Cryo ablation is performed on kidneys, lungs, bones, liver, as well as benign tumours such as breast fibroadenomas.

The procedures are covered for kidney tumours. The Cryo Ablation System is manufactured by Varian, the US manufacturer of the CryoCare Touch system.

Reversible electroporation

Reversible electroporation – electrochemotherapy – A combination of electrical impulses and anticancer drugs.Electrical impulses cause changes in the cell membrane: destabilisation of the cell membrane, the formation of temporary “pores” (electroporation), which increases the membrane’s permeability to substances on the outside of the membrane and allows the drug, which normally has difficulty penetrating the inside of the cell, to reach the target easily.

This approach allows the use of low doses to deliver an exceptionally high dose of chemopreparation to the tumour cell, while nearby healthy tissues, which are not very sensitive to the drug, remain intact. Electrochemotherapy has only been applied to superficial skin metastases, in particular breast cancer and melanoma. However, new systems have electrodes for deeper tissues, making it possible to treat pancreatic, liver, bone and other tumours. This method is special because it allows treatment of tumours in critical areas – near nerves and large blood vessels.During the procedure, two to six needles – electrodes – are inserted in and around the tumour, depending on the size of the tumour. A drug is then injected intravenously and the electrodes are activated. After a two-minute electroporation session, the concentration of the drug in the malignant cells increases by a factor of 1 000, the pores close and the drug slowly destroys the affected cells.

In Lithuania, electrochemotherapy is reimbursed from 2022.

AmberCell Solutions offers the Cliniporator VITAE electrochemotherapy system from the Italian company Igea, which can be used for both superficial tumours and parenchymal tumours.

Reverse electroporation procedure:

Radiofrequency ablation

Radiofrequency for ablation (RFA/RDA) –
is one of several ablation techniques used in medicine,
which is based on the application of a medium-frequency (350-500 kHz) alternating current to the desired tissue. The high temperatures generated during the procedure affect the histological structure of the desired tissue. RDA can be used alone or in combination with other treatments (surgery, chemotherapy, radiotherapy) to navic destroy, reduce. RDA can be used to treat liver, lung, kidney cancer. It is the oldest thermal ablations a treatment method pioneered a little more more more than twenty years ago.

Products

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CAS-One IR

Artificial intelligence navigation system developed by Swiss manufacturer CASCINATION to help plan, navigate and remove tumours during percutaneous interventions

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TATO

A device for microwave ablations created by the Japanese manufacturer TERUMO (up to four antennas at a time). Easy to operate, ergonomic and provides a safe procedure

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CRYOCARE TOUCH

US company VARIAN's system is designed to freeze tissue at ultra-low temperatures, and the cryoprobe can produce "ice balls" of various sizes

4

CLINIPORATION VITAE

The IGEA system from IGEA, an Italian company, is an electrochemotherapy system that can be used for both superficial tumours and parenchymal tumours

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