{"id":5842,"date":"2024-01-22T09:07:10","date_gmt":"2024-01-22T09:07:10","guid":{"rendered":"https:\/\/ambercell.pixel-dev.lt\/arstiem\/intervences-onkologija\/transareriska-kimijembolizacija-tace\/"},"modified":"2024-03-23T00:56:20","modified_gmt":"2024-03-23T00:56:20","slug":"transareriska-kimijembolizacija-tace","status":"publish","type":"page","link":"https:\/\/ambercell.eu\/lv\/arstiem\/intervences-onkologija\/transareriska-kimijembolizacija-tace\/","title":{"rendered":"Transarerisk\u0101 \u0137\u012bmijemboliz\u0101cija (TACE)"},"content":{"rendered":"\t\t
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Hepatocelul\u0101r\u0101 karcinoma (HCC) ir ceturtais izplat\u012bt\u0101kais v\u0113zis un tre\u0161ais galvenais ar v\u0113zi saist\u012bto n\u0101ves gad\u012bjumu c\u0113lonis pasaul\u0113. Transarterisk\u0101 \u0137\u012bmijemboliz\u0101cija (TACE) – minim\u0101li invaz\u012bva HCC un mCRC audz\u0113ju endovaskul\u0101ra \u0101rst\u0113\u0161ana.<\/span> <\/span>Starp da\u017e\u0101d\u0101m \u0101rst\u0113\u0161anas iesp\u0113j\u0101m trans-art\u0113risk\u0101 \u0137\u012bmijemboliz\u0101cija (TACE) ir efekt\u012bva izv\u0113le pacientiem ar HCC starpstadiju.<\/span>TACE ir vis\u0101 pasaul\u0113 pla\u0161i atz\u012bta metode neoperat\u012bvas vai vid\u0113jas stadijas HCC \u0101rst\u0113\u0161anai. <\/span> <\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Emboliz\u0101cija \u2013 asinsvada l\u016bmena da\u013cas vai visa asinsvada l\u016bmena nosprostojums, apturot asins pl\u016bsmu asinsvadu veidojumos<\/span>. Transarerisk\u0101 \u0137\u012bmijemboliz\u0101cija \u2013 TACE \u2013 apvieno \u0137\u012bmijterapijas z\u0101\u013cu viet\u0113jo pieg\u0101di ar emboliz\u0101ciju. \u0160\u012b proced\u016bra ir paredz\u0113ta aknu v\u0113\u017ea (HCC un mCRC) \u0101rst\u0113\u0161anai. Proced\u016bru veic invaz\u012bvais radiologs.<\/span> <\/span><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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HCC \u2013 (hepatocelul\u0101ra karcinoma) - hepatocelul\u0101ra hepatocelul\u0101ra karcinoma \u2013 hepatocelul\u0101ra hepatocelul\u0101ru \u0161\u016bnu karcinoma \u2013 visizplat\u012bt\u0101kais aknu v\u0113\u017ea veids, kas veido aptuveni 75-80 procentus. aknu v\u0113\u017ea gad\u012bjumi.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Hepatocelul\u0101ra karcinoma pieaugu\u0161ajiem att\u012bst\u0101s no hepatoc\u012btiem un bie\u017ei ir saist\u012bta ar hronisk\u0101m aknu slim\u012bb\u0101m. Slim\u012bbas s\u0101kum\u0101 att\u012bst\u0101s aknu iekaisums, ko var izrais\u012bt C vai B hepat\u012bta v\u012brusu infekcija, alkohola lieto\u0161ana, aptauko\u0161an\u0101s, retas aknu slim\u012bbas. P\u0113c tam iekaisuma izmai\u0146as progres\u0113 fibroz\u0113 un ciroz\u0113, kas var p\u0101rveidoties par pieaugu\u0161o hepatocelul\u0101ro karcinomu.<\/span><\/p>\n

Kolorekt\u0101lais v\u0113zis jeb “resn\u0101s zarnas” v\u0113zis ir viena no 5 visbie\u017e\u0101k sastopamaj\u0101m v\u0113\u017ea lokaliz\u0101cij\u0101m Lietuv\u0101. <\/span>\n \n<\/span>T\u0101pat k\u0101 daudzi citi, <\/span>\n \n<\/span> \u0161\u012b v\u0113\u017ea v\u0113\u017ea \u0161\u016bnas<\/span>\n \n<\/span> V\u0113zi var atdal\u012bt no audz\u0113ja un ce\u013cot uz citiem \u0137erme\u0146a org\u0101niem caur asinsvadiem vai limf\u0101tiskaj\u0101m sist\u0113m\u0101m. \u0160o procesu sauc par metast\u0101z\u0113m. Vairojas v\u0113\u017ea \u0161\u016bnas, kas ir sadziju\u0161as citos org\u0101nos, un veidojas jauni audz\u0113ji \u2013 metast\u0101zes.<\/span><\/span> \n Bie\u017ei vien<\/span> akn\u0101s tiek konstat\u0113tas <\/span> kolorekttal\u012bna<\/span>io<\/span> v\u0113\u017ea metast\u0101zes.M<\/span>\n \n \n \n \n<\/span>Etast\u0101zei akn\u0101s efekt\u012bva \u0101rst\u0113\u0161anas metode var b\u016bt <\/span>\n \n<\/span>TACE – lok\u0101la<\/span>\n \n<\/span> intraarteri\u0101la \u0137\u012bmijterapija akn\u0101m.<\/span>\n \n<\/span> <\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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TACE Lietuv\u0101<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Lietuv\u0101 \u0161\u012bs proced\u016bras jau vair\u0101k nek\u0101 desmit gadus tiek veiktas universit\u0101\u0161u slimn\u012bc\u0101s \u2013 LSMUL Kau\u0146as kl\u012bnik\u0101s, Klaip\u0113das Universit\u0101tes slimn\u012bc\u0101, VU Slimn\u012bcas Santarosas kl\u012bnik\u0101s, k\u0101 ar\u012b Nacion\u0101laj\u0101 v\u0113\u017ea instit\u016bt\u0101. <\/span> <\/span><\/p>\n

Izv\u0113loties hepatocelul\u0101r\u0101s (hepatocelul\u0101r\u0101s) karcinomas (HCC) \u0101rst\u0113\u0161anas metodi, ir \u013coti svar\u012bgi nov\u0113rt\u0113t ne tikai HCC radiolo\u0123isk\u0101s \u012bpa\u0161\u012bbas, bet ar\u012b aknu darb\u012bbu un pacienta funkcion\u0101lo st\u0101vokli. \u0160im nol\u016bkam tiek izmantots aknu v\u0113zis (aknu v\u0113zis) Barselonas kl\u012bnik\u0101. Barselonas kl\u012bnikas aknu v\u0113\u017ea (BCLC) stadijas krit\u0113riji.<\/span>Saska\u0146\u0101 ar \u0161\u012bm pamatnost\u0101dn\u0113m TACE var piem\u0113rot B posm\u0101. B stadijas (starpposma) gad\u012bjum\u0101 ieteicam\u0101 \u0101rst\u0113\u0161ana ir transarar\u012bna \u0137\u012bmijemboliz\u0101cija. Daudzi p\u0113t\u012bjumi apstiprina TACE agr\u012bn\u0101 un nedaudz progres\u012bv\u0101 stadij\u0101.<\/span><\/p>\n

BCLC 0. stadijas (\u013coti agr\u012bnas HCC) gad\u012bjum\u0101 TACE var\u0113tu b\u016bt alternat\u012bva pacientiem, kuri nav piem\u0113roti radiofrekvencei vai mikrovi\u013c\u0146u abl\u0101cijai, vai aknu rezekcijai. Pacientiem ar BCLC A stadiju kombin\u0113t\u0101 TACE un termisk\u0101s abl\u0101cijas metode nodro\u0161ina lab\u0101ku lok\u0101lo audz\u0113ja kontroli nek\u0101 tikai abl\u0101cija. TACE var izmantot k\u0101 “p\u0101rejas” terapiju pacientiem, kuri gaida aknu transplant\u0101ciju. Pacientiem ar B\u0160PV B TACE nodro\u0161ina izdz\u012bvo\u0161anas priek\u0161roc\u012bbas sal\u012bdzin\u0101jum\u0101 ar paliat\u012bv\u0101s \u0101rst\u0113\u0161anas iesp\u0113j\u0101m.<\/span> <\/span><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Proced\u016bru<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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TACE proced\u016bra tiek veikta invaz\u012bvo radiologu oper\u0101ciju z\u0101l\u0113 ar<\/span>ngiogr\u0101fiju<\/span>. P<\/span>er cirksnis, mikrosf\u0113ras tiek selekt\u012bvi ievad\u012btas asinsvad\u0101, kas baro audz\u0113ju ar \u012bpa\u0161u mikrokateri, kura virsma pirms proced\u016bras ir pies\u016bcin\u0101ta ar \u0137\u012bmijterapijas l\u012bdzekli<\/span>.<\/span> <\/span><\/p><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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TACE proced\u016bru prakse<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Kontroles<\/span>angiogr\u0101fija<\/span>a, angiogr\u0101fa<\/span> ekr\u0101n\u0101 <\/span>var redz\u0113t<\/span> audz\u0113ju, kas piepild\u012bts ar kontrastu<\/span><\/span>. \u0160\u012b ir \u0101rk\u0101rt\u012bgi prec\u012bza un dro\u0161a metode, kas \u013cauj ietekm\u0113t tikai audz\u0113ju, nesaboj\u0101jot ne tikai citus org\u0101nus, audus, bet ar\u012b p\u0101r\u0113jo veselo aknu da\u013cu. Z\u0101les, kas uzs\u016bcas uz mikrosf\u0113ru virsmas, iev\u0113rojami ilg\u0101k ietekm\u0113 v\u0113\u017ea aknu audus, sal\u012bdzinot ar <\/span>Cits __________ <\/span> \u0101rst\u0113\u0161anas metodes. Kad mikrosf\u0113ras non\u0101k audz\u0113ja mazajos asinsvados, tiek trauc\u0113ta asinsrite, att\u012bst\u0101s i\u0161\u0113mija un audz\u0113ja \u0161\u016bnu nekroze<\/span>.<\/span> <\/span><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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TACE fotogalerija<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Produkti<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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RADIFOCUS intorducer<\/a><\/h3>

Terumo ra\u017eot\u0101js ievada induc\u0113t\u0101jus ievieto\u0161anai caur \u0101du asinsvad\u0101, lai atvieglotu iejauk\u0161an\u0101s proced\u016bru<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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RADIFOCUS vads<\/a><\/h3>

TERUMO hidrof\u012blais virzo\u0161ais vads, p\u0101rkl\u0101ts ar poliuret\u0101nu, hidrof\u012blu polim\u0113ra p\u0101rkl\u0101jumu, lai vad\u012btu katetru uz v\u0113lamo vietu asinsvadu sist\u0113m\u0101 proced\u016bru laik\u0101.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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RADIFOCUS katetrs<\/a><\/h3>

Angiogr\u0101fijas vai diagnostikas TERUMO katetrs angiogr\u0101fijas proced\u016br\u0101m, ko izmanto kop\u0101 ar vadu: pieg\u0101d\u0101 radioakt\u012bvo vidi un materi\u0101lus uz izv\u0113l\u0113t\u0101m asinsvadu sist\u0113mas viet\u0101m.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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DZ\u012aVES P\u0112RLE<\/a><\/h3>

TERUMO izstr\u0101d\u0101t\u0101 z\u0101\u013cu izdal\u012bt\u0101 mikrosf\u0113ra LifePearl ir PEG (polietil\u0113nglikola) EMboliz\u0101cijas mikrosf\u0113ras, kur\u0101s var iel\u0101d\u0113t \u0137\u012bmijterapijas vielas <\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Minim\u0101li invaz\u012bva HCC un mCRC audz\u0113ju endovaskul\u0101ra \u0101rst\u0113\u0161ana. <\/p>\n

Emboliz\u0101cija \u2013 asinsvada l\u016bmena da\u013cas vai visa asinsvada l\u016bmena nosprostojums, apturot asins pl\u016bsmu asinsvadu veidojumos. Transarerisk\u0101 \u0137\u012bmijemboliz\u0101cija \u2013 TACE \u2013 apvieno \u0137\u012bmijterapijas z\u0101\u013cu viet\u0113jo pieg\u0101di ar emboliz\u0101ciju. \u0160\u012b proced\u016bra ir paredz\u0113ta aknu v\u0113\u017ea (HCC un mCRC) \u0101rst\u0113\u0161anai. Proced\u016bru veic invaz\u012bvais radiologs. <\/p>\n","protected":false},"author":8,"featured_media":5885,"parent":5625,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-5842","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"\nTransarerisk\u0101 \u0137\u012bmijemboliz\u0101cija (TACE) - Ambercell<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ambercell.eu\/lv\/arstiem\/intervences-onkologija\/transareriska-kimijembolizacija-tace\/\" \/>\n<meta property=\"og:locale\" content=\"lv_LV\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Transarerisk\u0101 \u0137\u012bmijemboliz\u0101cija (TACE) - Ambercell\" \/>\n<meta property=\"og:description\" content=\"Minim\u0101li invaz\u012bva HCC un mCRC audz\u0113ju endovaskul\u0101ra \u0101rst\u0113\u0161ana. Emboliz\u0101cija \u2013 asinsvada l\u016bmena da\u013cas vai visa asinsvada l\u016bmena nosprostojums, apturot asins pl\u016bsmu asinsvadu veidojumos. Transarerisk\u0101 \u0137\u012bmijemboliz\u0101cija \u2013 TACE \u2013 apvieno \u0137\u012bmijterapijas z\u0101\u013cu viet\u0113jo pieg\u0101di ar emboliz\u0101ciju. \u0160\u012b proced\u016bra ir paredz\u0113ta aknu v\u0113\u017ea (HCC un mCRC) \u0101rst\u0113\u0161anai. 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