{"id":10419,"date":"2025-04-09T07:19:58","date_gmt":"2025-04-09T07:19:58","guid":{"rendered":"https:\/\/ambercell.eu\/?page_id=10419"},"modified":"2025-04-09T07:49:55","modified_gmt":"2025-04-09T07:49:55","slug":"selektiva-intraarteriala-staru-terapija-sirt-2","status":"publish","type":"page","link":"https:\/\/ambercell.eu\/lv\/arstiem\/sirds-un-asinsvadu-slimibas\/selektiva-intraarteriala-staru-terapija-sirt-2\/","title":{"rendered":"Selekt\u012bv\u0101 intraarteri\u0101l\u0101 staru terapija (SIRT)"},"content":{"rendered":"\t\t
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Inovat\u012bva selekt\u012bva intraarteri\u0101la staru terapija (SIRT) ir v\u0113\u017ea \u0101rst\u0113\u0161anas metode, kuras laik\u0101 tiek veikta aknu audz\u0113ja asinsvadu emboliz\u0101cija (blo\u0137\u0113\u0161ana) ar radioakt\u012bv\u0101m da\u013ci\u0146\u0101m.
\nSIRT proced\u016bras tiek izmantotas ne\u0137irur\u0123isku (nav piem\u0113rots operat\u012bvai \u0101rst\u0113\u0161anai) aknu audz\u0113ju un aknu metast\u0101\u017eu gad\u012bjumos. Emboliz\u0101cija \u2013 asinsvada l\u016bmena da\u013cas vai visa asinsvada l\u016bmena nosprostojums, apturot asins pl\u016bsmu asinsvadu veidojumos.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Radioemboliz\u0101cija ar Holmium-166 radioizotopu.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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P\u0113c proced\u016bras ar radioakt\u012bvu materi\u0101lu tiek m\u0113r\u012bts pacienta izstarot\u0101s radioaktivit\u0101tes fons. Ja pacients tiek \u0101rst\u0113ts ar viet\u0113j\u0101s \u0101rst\u0113\u0161anas metodi, radioaktivit\u0101te tiek lokaliz\u0113ta viet\u0101, kur t\u0101 tiek injic\u0113ta. P\u0113c proced\u016bras tika m\u0113r\u012bts liel\u0101ks radioaktivit\u0101tes fons, t\u0101p\u0113c pacienta izol\u0101cijas pas\u0101kumi tiek piem\u0113roti uz noteiktu laiku – pacients paliek atsevi\u0161\u0137\u0101 pal\u0101t\u0101 vienu dienu, l\u012bdz vi\u0146\u0161 k\u013c\u016bst dro\u0161s videi un var atgriezties m\u0101j\u0101.<\/span><\/span> <\/span><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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SIRT pieteikums<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Starptautisk\u0101s vadl\u012bnijas iesaka SIRT k\u0101 vienu no <\/span>HCC un mCRC audz\u0113ju<\/span> \u0101rst\u0113\u0161anas metod\u0113m<\/span>. T\u0101s m\u0113r\u0137i ir \u0161\u0101di:<\/span> palielin\u0101t kop\u0113jo dz\u012bvildzi pacientiem ar progres\u0113jo\u0161as<\/span>stadijas hCC audz\u0113jiem<\/span> , kuriem iepriek\u0161\u0113j\u0101s \u0101rst\u0113\u0161anas<\/span>metodes nav biju\u0161as veiksm\u012bgas. <\/span><\/span><\/p>\n

Pacientiem agr\u012bn\u0101 stadij\u0101 ar HCC SIRT m\u0113r\u0137is ir ar\u012b nodro\u0161in\u0101t terapeitisku \u0101rst\u0113\u0161anu, piem\u0113ram<\/span>, “savieno\u0161anu” <\/span> pirms transplant\u0101cijas, pied\u0101v\u0101jot audz\u0113ja kontroli, lai pacients paliktu transplant\u0101cijas gaid\u012b\u0161anas sarakst\u0101<\/span> uz ilg\u0101ku laiku. To var izmantot ar\u012b, lai samazin\u0101tu audz\u0113jus pacientiem rezekcijai<\/span>.<\/span><\/span> <\/span>
<\/span><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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SIRT proced\u016bra<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Radioemboliz\u0101cijas proced\u016bra sast\u0101v no 2 posmiem \u2013 diagnostikas un \u0101rst\u0113\u0161anas stadijas. Abu posmu gaita ir vien\u0101da, at\u0161\u0137iras tikai injic\u0113to radioizotopu daudzums. Diagnostikas f\u0101zes laik\u0101 tiek ievad\u012bta neliela radioakt\u012bv\u0101 prepar\u0101ta deva. \u0160is posms ir paredz\u0113ts, lai prec\u012bzi redz\u0113tu, kur\u0101s viet\u0101s prepar\u0101ts non\u0101k, lai pacients var\u0113tu veikt dro\u0161u terapeitisko proced\u016bru. Lai sasniegtu vislab\u0101ko iesp\u0113jamo efektu, ar \u012bpa\u0161u programmu pal\u012bdz\u012bbu tiek apr\u0113\u0137in\u0101ts, k\u0101da deva ir nepiecie\u0161ama konkr\u0113tam fokusam un konkr\u0113tam pacientam. T\u0101d\u0101 veid\u0101 pacients tiek pak\u013cauts personaliz\u0113tai \u0101rst\u0113\u0161anai, kad vi\u0146a taktika ir z\u0101\u013cu deva un \u0101rst\u0113jam\u0101s vietas izv\u0113le personaliz\u0113t\u0101 veid\u0101. <\/span> <\/span><\/p>\n<\/p>\n

Zemas invaz\u012bvas iejauk\u0161an\u0101s proced\u016bras laik\u0101 holmija mikrosf\u0113ras izplat\u0101s audz\u0113ja audos, un izotopa izstarotais beta starojums ietekm\u0113 audz\u0113ja biolo\u0123iju un veicina audz\u0113ja \u0161\u016bnu n\u0101vi. Holmio izotopam ir unik\u0101las \u012bpa\u0161\u012bbas, kas papildus izstaro zemas ener\u0123ijas gamma starojumu un paramagn\u0113tisko starojumu, pateicoties kuriem izotops ir redzams diagnostikas iek\u0101rt\u0101s. Tas \u013cauj prec\u012bzi pl\u0101not proced\u016bru un apr\u0113\u0137in\u0101t individu\u0101li izrakst\u012bt\u0101s radioaktivit\u0101tes devu, lai \u0101rst\u0113\u0161ana b\u016btu veiksm\u012bg\u0101ka un tai neb\u016btu nopietnu blakuspar\u0101d\u012bbu<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Sirt kurss un \u0101rst\u0113\u0161anas scen\u0101riji<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Strauji augo\u0161iem aknu audz\u0113jiem ir daudz barojo\u0161u asinsvadu, tie\u0161i \u0161o \u012bpa\u0161\u012bbu \u0101rsti cen\u0161as izmantot. Vi\u0146u uzdevums ir identific\u0113t asinsvadus un izmantot \u012bpa\u0161as navig\u0101cijas angiogr\u0101fisk\u0101s programmas, lai tos ievad\u012btu. \u0100rst\u0113\u0161anas laik\u0101 tiek caurdurta rokas vai aug\u0161stilba art\u0113rija, aknu art\u0113rij\u0101s non\u0101k speci\u0101li vado\u0161ie katetri, un pat pl\u0101n\u0101ki mikrokatetri (0,6-0,8 mm diametr\u0101) sasniedz art\u0113rijas, kas baro audz\u0113ju, un ar asins pl\u016bsmu l\u0113n\u0101m tiek injic\u0113tas radioakt\u012bv\u0101s da\u013ci\u0146as. Prec\u012bzi apr\u0113\u0137in\u0101tais da\u013ci\u0146u daudzums “iestr\u0113gst” audz\u0113ja mikroplais\u0101s, notiek iek\u0161\u0113j\u0101 apstaro\u0161ana – radioaktivit\u0101te izn\u012bcina tuvum\u0101 eso\u0161\u0101s audz\u0113ja \u0161\u016bnas.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Tabula: Da\u017e\u0101di kl\u012bniskie scen\u0101riji SIRT lieto\u0161anai HCC, kas nosaka MAA anal\u012bzes lietder\u012bbu<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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SIRT proced\u016bru prakse<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Tiek veikta kontroles angiogr\u0101fija, kuras laik\u0101 tiek nov\u0113rots audz\u0113js, kas piepild\u012bts ar kontrastu.
\nSelekt\u012bv\u0101 intraarteri\u0101l\u0101 staru terapija (SIRIT) ir \u0101rk\u0101rt\u012bgi prec\u012bza un dro\u0161a metode, kas \u013cauj ietekm\u0113t tikai audz\u0113ju, nesaboj\u0101jot citus org\u0101nus, audus, bet ar\u012b p\u0101r\u0113jo veselo aknu da\u013cu.
\nZ\u0101l\u0113m, kas uzs\u016bcas uz mikrosf\u0113ru virsmas, ir iev\u0113rojami ilg\u0101ka ietekme uz v\u0113\u017ea aknu audiem, sal\u012bdzinot ar cit\u0101m aknu v\u0113\u017ea \u0101rst\u0113\u0161anas metod\u0113m.
\nKad mikrosf\u0113ras non\u0101k audz\u0113ja mazajos asinsvados, tiek trauc\u0113ta asinsrite, att\u012bst\u0101s i\u0161\u0113mija un audz\u0113ja \u0161\u016bnu nekroze. <\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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SIRT fotogalerija<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Radioemboliz\u0101cija ir viens no viet\u0113j\u0101s terapijas veidiem kop\u0161 2022. gada. Iek\u013cauts starptautiskaj\u0101s aknu v\u0113\u017ea \u0101rst\u0113\u0161anas rokasgr\u0101mat\u0101s. \u0160\u012b proced\u016bra Lietuv\u0101 tiek kompens\u0113ta no oblig\u0101t\u0101s vesel\u012bbas apdro\u0161in\u0101\u0161anas bud\u017eeta. <\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Produkti<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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QUIREM SF\u0112RAS<\/a><\/h3>

Holmium platforma TERUM organiz\u0101cijai ir pirm\u0101 SIRT: visaptvero\u0161a platforma neoper\u0113jamu aknu audz\u0113ju \u0101rst\u0113\u0161anai. Quiremspheres\u2122: vien\u012bg\u0101 SIRT terapeitisk\u0101 mikrosf\u0113ra, ko izmanto k\u0101 da\u013cu no piln\u012bb\u0101 integr\u0113tas platformas<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\"10\"<\/a><\/figure>

OCCLUSAFE<\/a><\/h3>

Terumo ra\u017eot\u0101ja okluz\u012bvais balonu mikrokataters sniedz iesp\u0113ju p\u0101rdal\u012bt asins pl\u016bsmu un pan\u0101kt mikrocirkul\u0101ciju, kas palielina \u0101rstniecisko vielu uzkr\u0101\u0161anos m\u0113r\u0137a boj\u0101jum\u0101 un samazina nem\u0113r\u0137a emboliz\u0101ciju.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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PROGREAT <\/a><\/h3>

TERUMO mikrokatetrs ar integr\u0113tu vadu terapeitiskai emboliz\u0101cijai un angiogr\u0101fijai perif\u0113rajos asinsvados. Lieto\u0161anas \u0113rtums, iztur\u012bba pret saliekumiem, dist\u0101l\u0101 elast\u012bba<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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ANGIO SEAL VIP<\/a><\/h3>

Angio-Seal\u2122 VIP krustenisko v\u0113nu sl\u0113g\u0161anas ier\u012bce sl\u0113g\u0161anai un laika l\u012bdz hemost\u0101zes sa\u012bsin\u0101\u0161anai kop\u0113j\u0101s aug\u0161stilba art\u0113rijas punkcijas viet\u0101 pacientiem, kuriem tiek veikta diagnostisk\u0101 angiogr\u0101fija vai intervences proced\u016bras.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Radioemboliz\u0101cija \u2013 v\u0113\u017ea \u0101rst\u0113\u0161anas metode, kad tiek veikta aknu audz\u0113ja asinsvadu emboliz\u0101cija (blo\u0137\u0113\u0161ana) ar radioakt\u012bv\u0101m da\u013ci\u0146\u0101m. \u0160o \u0101rst\u0113\u0161anas metodi izmanto neoperat\u012bvu (nav piem\u0113rots operat\u012bvai \u0101rst\u0113\u0161anai) aknu audz\u0113ju un aknu metast\u0101\u017eu gad\u012bjumos. Emboliz\u0101cija \u2013 asinsvada l\u016bmena da\u013cas vai visa asinsvada l\u016bmena nosprostojums, apturot asins pl\u016bsmu asinsvadu veidojumos.<\/p>\n","protected":false},"author":5,"featured_media":10626,"parent":5299,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-10419","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"\nSelekt\u012bva intraartikul\u0101ra staru terapija | AmberCell<\/title>\n<meta name=\"description\" content=\"Inovat\u012bva selekt\u012bva intraarteri\u0101la staru terapija HCC un mCRC audz\u0113ju \u0101rst\u0113\u0161anai. 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