{"id":5735,"date":"2024-01-22T09:07:10","date_gmt":"2024-01-22T09:07:10","guid":{"rendered":"https:\/\/ambercell.pixel-dev.lt\/arstide-jaoks\/sekkuv-onkoloogia\/transarteriline-kemoemboolia-tace\/"},"modified":"2024-03-23T00:56:19","modified_gmt":"2024-03-23T00:56:19","slug":"transarteriline-kemoemboolia-tace","status":"publish","type":"page","link":"https:\/\/ambercell.eu\/et\/arstide-jaoks\/sekkuv-onkoloogia\/transarteriline-kemoemboolia-tace\/","title":{"rendered":"Transarteriline kemoemboolia (TACE)"},"content":{"rendered":"\t\t
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Hepatotsellulaarne kartsinoom (HCC) on neljas k\u00f5ige levinum v\u00e4hk ja kolmas peamine v\u00e4higa seotud surmade p\u00f5hjus maailmas. Transarteriline kemoemboolia (TACE) – HCC ja mCRC kasvajate minimaalselt invasiivne endovaskulaarne ravi.<\/span> <\/span>Erinevate raviv\u00f5imaluste hulgas on transarteriaalne kemoemboolia (TACE) t\u00f5hus valik HCC vahefaasiga patsientidele.<\/span>TACE on laialdaselt tunnustatud \u00fclemaailmne meetod mitteoperatiivse v\u00f5i keskmise staadiumi HCC raviks. <\/span> <\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Emboliseerimine \u2013 veresoone valendiku osa v\u00f5i veresoone kogu valendiku blokeerimine, verevoolu peatamine veresoonte moodustumisel<\/span>. Transarteriline kemoemboolia – TACE – \u00fchendab kemoterapeutilise ravimi kohaliku pakkumise emboliseerimisega. See protseduur on ette n\u00e4htud maksav\u00e4hi (HCC ja mCRC) raviks. Protseduuri viib l\u00e4bi sekkuv radioloog.<\/span> <\/span><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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HCC - (hepatotsellulaarne kartsinoom) - hepatotsellulaarne hepatotsellulaarne kartsinoom - hepatotsellulaarne hepatotsellulaarne kartsinoom - k\u00f5ige levinum maksav\u00e4hi t\u00fc\u00fcp, moodustades umbes 75-80 protsenti. maksav\u00e4hi juhtumid.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Hepatotsellulaarne kartsinoom t\u00e4iskasvanutel areneb hepatots\u00fc\u00fctidest ja on sageli seotud krooniliste maksahaigustega. Haiguse alguses areneb maksap\u00f5letik, mida v\u00f5ib p\u00f5hjustada C- v\u00f5i B-hepatiidi viirusinfektsioon, alkoholi kuritarvitamine, rasvumine, haruldased maksahaigused. Seej\u00e4rel progresseeruvad p\u00f5letikulised muutused fibroosiks ja tsirroosiks, mis v\u00f5ib muutuda t\u00e4iskasvanud hepatotsellulaarseks kartsinoomiks.<\/span><\/p>\n

Kolorektaalne v\u00e4hk v\u00f5i “k\u00e4\u00e4rsoolev\u00e4hk” on \u00fcks 5-st k\u00f5ige levinumast v\u00e4hi lokaliseerimisest Leedus. <\/span>\n \n<\/span>Nagu paljud teisedki, <\/span>\n \n<\/span> on selle v\u00e4hi v\u00e4hirakud<\/span>\n \n<\/span> V\u00e4hk v\u00f5ib kasvajast eralduda ja liigub veresoonte v\u00f5i l\u00fcmfis\u00fcsteemi kaudu teistesse keha organitesse. Seda protsessi nimetatakse metastaasideks. Teistes elundites paranenud v\u00e4hirakud paljunevad ja moodustuvad uued kasvajad \u2013 metastaasid.<\/span><\/span> \n Sageli<\/span> tuvastatakse maksas <\/span> kolorektaliini<\/span>io<\/span> v\u00e4hi metastaasid.M<\/span>\n \n \n \n \n<\/span>Maksa etastaasi korral v\u00f5ib efektiivne ravimeetod olla <\/span>\n \n<\/span>TACE – lokaalne<\/span>\n \n<\/span> arteriaalne keemiaravi maksas.<\/span>\n \n<\/span> <\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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TACE Leedus<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Leedus on neid protseduure tehtud juba \u00fcle k\u00fcmne aasta \u00fclikoolihaiglates \u2013 LSMUL Kaunase kliinikus, Klaip\u0117da \u00fclikooli kliinikus, VU haigla Santaros kliinikus ja riiklikus v\u00e4hiinstituudis. <\/span> <\/span><\/p>\n

Hepatotsellulaarse (hepatotsellulaarse) kartsinoomi (HCC) ravimeetodi valimisel on v\u00e4ga oluline hinnata mitte ainult HCC radioloogilisi omadusi, vaid ka maksafunktsiooni ja patsiendi funktsionaalset seisundit. Selleks kasutatakse Barcelona kliinikus maksav\u00e4hki (maksav\u00e4hki). Barcelona kliiniku maksav\u00e4hi (BCLC) etapiviisilised kriteeriumid.<\/span>Nende suuniste kohaselt v\u00f5ib TACEd kohaldada B etapis. B-etapi (vahepealne) korral on soovitatav ravi transarteriline kemoemboolia. Paljud uuringud kinnitavad TACE-d varases ja veidi arenenud staadiumis.<\/span><\/p>\n

BCLC 0. etapis (v\u00e4ga varajane HCC) v\u00f5ib TACE olla alternatiiv patsientidele, kes ei sobi raadiosageduslikuks v\u00f5i mikrolaine ablatsiooniks v\u00f5i maksa resektsiooniks. BCLC A-staadiumiga patsientidel tagavad kombineeritud TACE ja termilise ablatsiooni meetod parema lokaalse kasvaja kontrolli kui ainult ablatsioon. TACE-d saab kasutada “sildravina” maksasiirdamist ootavate patsientide jaoks. BCLC B-GA PATSIENTIDELE annab TACE elluj\u00e4\u00e4mise eelise palliatiivsete raviv\u00f5imaluste ees.<\/span> <\/span><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Menetlus<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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TACE protseduur viiakse l\u00e4bi sekkuvate radioloogide operatsioonisaalis<\/span>ngiograafia<\/span>. P<\/span>er kubemes, mikrosf\u00e4\u00e4rid viiakse selektiivselt veresoonde, mis toidab kasvajat spetsiaalse mikrokateetriga, mille pind immutatakse enne protseduuri kemoterapeutilise ainega<\/span>.<\/span> <\/span><\/p><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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TACE menetluspraktika<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Kontrollangiograafia<\/span>a, angiograafi<\/span> ekraanil <\/span>n\u00e4ete<\/span> kontrastiga<\/span> t\u00e4idetud kasvajat<\/span><\/span>. See on \u00e4\u00e4rmiselt t\u00e4pne ja ohutu meetod, mis v\u00f5imaldab teil m\u00f5jutada ainult kasvajat, kahjustamata mitte ainult teisi elundeid, kudesid, vaid ka \u00fclej\u00e4\u00e4nud maksa tervislikku osa. Ravimil, mis imendub mikrosf\u00e4\u00e4ride pinnale, on v\u00e4hkkasvaja maksakoele oluliselt pikem toime kui <\/span>Muu <\/span> ravimeetodid. Kui mikrosf\u00e4\u00e4rid sisenevad kasvaja v\u00e4ikestesse veresoontesse, h\u00e4iritakse vereringet, tekib kasvajarakkude isheemia ja nekroos<\/span>.<\/span> <\/span><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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TACE fotogalerii<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Tooted<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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RADIFOCUS intorducer<\/a><\/h3>

Terumo tootja tutvustab sekkumisprotseduuri h\u00f5lbustamiseks naha kaudu veresoonde sisestamist<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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RADIFOCUS traat<\/a><\/h3>

TERUMO h\u00fcdrofiilne juhtetraat, mis on kaetud pol\u00fcuretaaniga, h\u00fcdrofiilse pol\u00fcmeerikattega, kateetri juhtimiseks protseduuride ajal soovitud kohta veresoones.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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RADIFOCUS kateeter<\/a><\/h3>

Angiograafiline v\u00f5i diagnostiline TERUMO-kateeter angiograafilisteks protseduurideks, mida kasutatakse koos juhtetraadiga: toimetab radioaktiivseid aineid ja materjale valitud kohtadesse veres\u00fcsteemis.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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ELU P\u00c4RL<\/a><\/h3>

TERUMO poolt v\u00e4lja t\u00f6\u00f6tatud ravimi sekreteeritud mikrosf\u00e4\u00e4r LifePearl on PEG-i (pol\u00fcet\u00fcleengl\u00fckooli) EMboliseerimise mikrosf\u00e4\u00e4rid, kuhu saab laadida kemoterapeutilisi aineid <\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t<\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\tK\u00f5ik tooted<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

HCC ja mCRC kasvajate minimaalselt invasiivne endovaskulaarne ravi. <\/p>\n

Emboliseerimine \u2013 veresoone valendiku osa v\u00f5i veresoone kogu valendiku blokeerimine, veresoonte moodustumise peatamine. Transarteriline kemoemboolia – TACE – \u00fchendab kemoterapeutilise ravimi kohaliku pakkumise emboliseerimisega. See protseduur on ette n\u00e4htud maksav\u00e4hi (HCC ja mCRC) raviks. Protseduuri viib l\u00e4bi sekkuv radioloog. <\/p>\n","protected":false},"author":8,"featured_media":5773,"parent":5617,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-5735","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"\nTransarteriline kemoemboolia (TACE) - Ambercell<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ambercell.eu\/et\/arstide-jaoks\/sekkuv-onkoloogia\/transarteriline-kemoemboolia-tace\/\" \/>\n<meta property=\"og:locale\" content=\"et_EE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Transarteriline kemoemboolia (TACE) - Ambercell\" \/>\n<meta property=\"og:description\" content=\"HCC ja mCRC kasvajate minimaalselt invasiivne endovaskulaarne ravi. Emboliseerimine \u2013 veresoone valendiku osa v\u00f5i veresoone kogu valendiku blokeerimine, veresoonte moodustumise peatamine. Transarteriline kemoemboolia - TACE - \u00fchendab kemoterapeutilise ravimi kohaliku pakkumise emboliseerimisega. See protseduur on ette n\u00e4htud maksav\u00e4hi (HCC ja mCRC) raviks. 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Emboliseerimine \u2013 veresoone valendiku osa v\u00f5i veresoone kogu valendiku blokeerimine, veresoonte moodustumise peatamine. Transarteriline kemoemboolia - TACE - \u00fchendab kemoterapeutilise ravimi kohaliku pakkumise emboliseerimisega. See protseduur on ette n\u00e4htud maksav\u00e4hi (HCC ja mCRC) raviks. 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